Table 9: AUC comparison of Savonix subtests with the lower and higher reference AUCs. For Normal vs. MCI discrimination.
Tests in bold: Selected tests to detect MCI from Normal. AUC: Area under the ROC curve. CI: confidence interval. *: p value of DeLong’s ROC comparison tests.
Tests AUC (95% CI) Comparison with MinAUC (Verbal Interference Part 1’s)
p value*
Comparison with MaxAUC (AUC for Total 6 Domain score: 0.800)
p value
Immediate Verbal Learning 0.684 (0.571-0.798) p < 0.05 p<001
Delayed Verbal Learning 0.720 (0.616-0.823) p<0.01 p<0.05
Verbal Interference Part 1 0.469 (0.352-0.586)
Verbal Interference Part 2 0.485 (0.377-0.593) p=0.81 n.s. p<0.001
Trail Making Part 1 0.724 (0.645-0.804) P<0.001 p<0.05
Trail Making Part 2 0.742 (0.652-0.831) P<0.001 p=0.111 n.s.
Digit Span Forward 0.551 (0.439-0.662) p=0.366 n.s. p<0.0001
Digit Span Reverse 0.557 (0.454-0.660) p=0.223 n.s. p<0.001
Maze 1 0.603 (0.510-0.697) P=0.081 n.s P<0.01
Maze 2 0.718 (0.621-0.815) p<0.001 P=0.190 n.s.
Complex Figure 0.745 (0.665-0.825) P<0.001 P=0.08n.s.