Table 1: Population characteristics according to clinical diagnosis and cognitive assessment.
*: p value of one-way ANOVA for Age and Education Years. p value of Chi-squared test for Gender. p value of t-test for MMSE, ADAS-Cog, and CDRSB.
Characteristics Normal (N=265) MCI (N=28) AD (N=21) Comparison test P value* Univariate logistic regression P value
Age, mean (SD) 62.3 (8.00) 72.14 (8.20) 72.57 (7.00) < 0.0001 < 0.0001 for Normal vs. MCI
< 0.0001 for Normal vs. AD
< 0.0001 for Normal vs. MCI/AD
0.844 for MCI vs. AD
Gender, number of female (%) 191 (72.1) 15 (53.6) 11 (52.4) 0.891 NA
Education Years, mean (SD) 10.43 (2.39) 11.57 (3.94) 13.38 (2.46) < 0.001 < 0.0001 for Normal vs. MCI
< 0.05 for Normal vs. AD
< 0.0001 for Normal vs. MCI/AD
< 0.1 for MCI vs. AD
MMSE total score, mean (SD) 27.64 (1.39) 22.29 (2.12) < 0.0001 < 0.05
ADAS-Cog total score, mean (SD) 16.36 (4.96) 23.14 (8.47) < 0.01 < 0.001
CDRSB, mean (SD) 1.61 (1.07) 2.95 (1.77) < 0.01 < 0.01