Table 4: Parameters for insulin action and secretion before and after treatment of responder and non-responders.

	Before Treatment			After Treatment
	Non-responder	Responder	p-valuec	Non-responder	Responder	p-valuec
First phase insulin secretion a	19.2 (7.5-40.6)	12.4 (5.1-40.7)	NS	46.0 (20.8-70.7)	50.0 (2.4-72.1)	NS
Second phase insulin secretion b	0.082 (0.058-0.107)	0.006(-0.0006-0.045)	0.0019	0.063 (0.015-0.077)	0.096 (0.063-0.127)d	0.0492
HOMA-IR	0.96 (0.47-1.36)	0.68 (0.22-3.04)	NS	0.85 (0.52-2.95)	1.2 (0.75-2.84)	NS
HOMA-B	5.36 (1.26-17.75)	-0.25 (-1.81-4.14)	0.0651	4.74 (4.41-18.8)	8.17 (3.41-13.74)d	NS
Insulin sensitivity	4.5 (1.8-5.4)	1.8 (1.0-2.5)	NS	2.6 (1.3-3.1)	2.1 (1.6-6.2)	NS