The Response of First and Second Phase Insulin Secretion in Newly Diagnosed Type 2 Diabetes Mellitus : Table 3

Table 3: Comparison of clinical and metabolic characteristics of responders and non-responders before and after treatment.

Adjusted for age and gender; Data shown as mean ± standard division;
HDL-C: high-density lipoprotein-cholesterol.
NS= : non-significant, responders v.s. non-responders.
^a responders v.s. non-responders.
^b p<0.05 before treatment v.s. after treatment.

		Non-responders	Responders	p value ^a
n		13	14
Age		56±9.6	46.9±6.7	0.003
Male (n, %)		4 (30.8)	7 (50)	0.440
Body mass index(kg/m2)	before	26.4±3.5	23.7±2.2	0.002
Body mass index(kg/m2)	after	27.3±4.3	24.5±3.0_b	0.01
Waist circumference(cm)	before	83.8±6.7	79. 3±6.8	0.035
Waist circumference(cm)	after	84.6±7.3	82.3±8.0	NS
Hip circumference (cm)	before	95.5±8.2	90.8±6.5	0.071
Hip circumference (cm)	after	99.7±7.7^b	96.1±7.3b	0.053
Waist-hip ratio	before	0.88±0.04	0.87±0.04	NS
Waist-hip ratio	after	0.85±0.06	0.86±0.04	NS
Systolic blood pressure (mmHg)	before	122±13	125±20	NS
Systolic blood pressure (mmHg)	after	122±12	120±10	NS
Diastolic blood pressure (mmHg)	before	74±7	77±10	NS
Diastolic blood pressure (mmHg)	after	77±7	82±7b	NS
Fasting plasma glucose (mg/dl)	before	123±44	181±68	0.044
Fasting plasma glucose (mg/dl)	after	117±26	130±41^b	NS
Fasting insulin (pmol/L)	before	4.7±5.3	3.6±5.0	NS
Fasting insulin (pmol/L)	after	6.4±6.8	5.5±4.7	NS
Hemoglobin A1c (%)	before	8.1 ±1.5	11.1 ±2.3	0.004
Hemoglobin A1c (%)	after	7.1±1.1^b	7.9±1.8b	NS
Total Cholesterol (mmol/L)	before	4.03±0.70	4.14 ±0.96	NS
Total Cholesterol (mmol/L)	after	4.59±0.67^b	4.17±0.68	NS
Triglyceride (mmol/L)	before	1.33±0.30	1.89±1.61	NS
Triglyceride (mmol/L)	after	1.52±0.41	1.69±0.70	NS
HDL-C (mmol/L)	before	1.11±0.21	1.03 ±0.37	NS
HDL-C (mmol/L)	after	1.42±0.37^b	1.10±0.24^b	NS