Table 6: Effects of polyphenolic compounds from pine bark extract on the ratio of erythrocytic reduced glutathione/oxidized glutathione in attention-deficit hyperactive disorder participants.
Values are expressed as the mean ± SD. B: baseline, before supplementation; P: placebo, 4-week supplementation with maltodextrin and magnesium stearate; PE: 4-week supplementation with polyphenolic compounds from pine bark extract; GSH: reduced glutathione; GSSG: oxidized glutathione; TBARS: 2-thiobarbituric acid-reactive substance.
| B | P | PE | p value |
| B x P | B x PE | P x PE |
| Erythrocytic GSH/GSSG ratio | 3.8 ± 1.7 | 4.3 ± 2.1 | 4.3 ± 1.8 | 0.466 | 0.355 | 0.964 |
| Plasma TBARS (μM) | 8.7 ± 4.1 | 9.6 ± 7.5 | 6.8 ± 4.8 | 0.100 | 0.880 | 0.168 |
| Plasma 8-isoprostane (pg/mL) | 52.1 ± 23.4 | 54.3 ± 25.7 | 43.8 ± 33.8 | 0.834 | 0.398 | 0.332 |