Table 3: Effects of polyphenolic compounds from pine bark extract on CPT-III in attention-deficit hyperactive disorder participants.
Values are expressed as the mean ± SD. B: baseline, before supplementation; P: placebo, 4-week supplementation with maltodextrin and magnesium stearate; PE: 4-week supplementation with polyphenolic compounds from pine bark extract; CPT-III: continuous performance test III; HRT: hit reaction time; HRT-SD: hit reaction time-standard deviation; HRT-BC: hit reaction time-block change; HRT-ISI-C: hit reaction time-inter-stimulus interval-change.
T-score p value
B P PE B x P B x PE P x PE
Inattention
Detectability 47.5 ± 9.4 46.0 ± 7.6 45.5 ± 9.8 0.508 0.460 0.821
Omissions 46.2 ± 4.1 46.0 ± 2.1 47.3 ± 4.9 0.829 0.556 0.387
Commissions 52.2 ± 11.5 48.2 ± 9.6 47.3 ± 9.1 0.138 0.099 0.672
HRT 47.8 ± 7.3 49.4 ± 8.8 51.8 ± 9.0 0.321 0.053 0.057
HRT-SD 47.9 ± 10.4 46.1 ± 7.8 50.1 ± 12.0 0.281 0.342 0.060
Variability 46.6 ± 7.4 45.0 ± 5.0 47.4 ± 10.1 0.427 0.807 0.363
Impulsivity
Commissions 52.2 ± 11.5 48.2 ± 9.6 47.3 ± 9.1 0.138 0.099 0.672
HRT 47.8 ± 7.3 49.4 ± 8.8 51.8 ± 9.0 0.321 0.053 0.057
Perseverations 48.1 ± 3.1 47.3 ± 3.2 48.5 ± 5.1 0.419 0.797 0.396
Sustained attention
HRT-BC 48.3 ± 8.9 51.5 ± 6.2 53.5 ± 14.7 0.270 0.383 0.634
Vigilance
HRT-ISI-C 55.4 ± 11.1 57.0 ± 9.3 57.9 ± 6.7 0.262 0.228 0.428